13: Episode 13 – Serotonin Syndrome: When Medications Go Wrong

Most of us carry and commonly administer medications that affect the neurotransmitter serotonin (e.g. Fentanyl). Additionally, most of our patients with a history of depression and/or anxiety are prescribed selective serotonin reuptake inhibitors (SSRI’s). In this episode, we discuss Serotonin Syndrome: a dangerous condition precipitated by the combined use of these commonly administered serotonergic drugs.  Tune in as we discuss various drug combinations, the mechanism driving the resulting signs/symptoms, and the treatment course we should take to reverse these adverse effects.

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